Before I describe the results, I should explain that a long history of research in psychology and of observations in clinical neurology prompted this experiment. Psychologists had experimented extensively with visual deprivation in animals in the 1940s and 1950s, using behavioral methods to assess the effects. A typical experiment was to bring animals up from birth in complete darkness. When the animals were brought out into the light, they turned out to be blind or at least very defective visually. The blindness was to some extent reversible, but only slowly and not in most cases completely. Paralleling these experiments were clinical observations on children born with cataracts. A cataract is a condition in which the lens of the eye becomes milky, transmitting light but no longer permitting an image to form on the retina. Cataracts in newborns, like those in adults, are treated by removing the lenses surgically and compensating by fitting the child with an artificial lens implant or with thick glasses. In that way, a perfectly focused retinal image can be restored. Although the operation is relatively easy, ophthalmologists have been loath to do it in very young infants or babies, mainly because any operation at a very early age carries more risk statistically, although the risk is small. When cataracts were removed, say at an age of eight years, and glasses fitted, the results were bitterly disappointing. Eyesight was not restored at all: the child was blind as ever, and profound deficits persisted even after months or years of attempts to learn to see. A child would, for example, continue to be unable to tell a circle from a triangle. With hopes thus raised and dashed, the child was generally worse off, not better. We can contrast this with clinical experience in adults: a man of seventy-five develops cataracts and gradually loses sight in both eyes. After three years of blindness the cataracts are removed, glasses fitted, and vision is completely restored. The vision can even be better than it was before the cataracts developed, because all lenses yellow with age, and their removal results in a sky of marvelous blue seen otherwise only by children and young adults. It would seem that visual deprivation in children has adverse effects of a sort that do not occur at all in adults. Psychologists commonly and quite reasonably attributed the results of their experiments, as well as the clinical results, to a failure of the child to learn to see or, presumably the equivalent, to a failure of connections to develop for want of some kind of training experience.